Demethylation, Methylation and 3'-Hydroxylation of Isoflavones bv Fusarium Fungi
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چکیده
Isoflavones, Fusarium, Methylation, Demethylation, 3'-Hydroxylation, Metabolism Several introductionary reactions of isoflavone metabolism by Fusarium fungi are reported. Fu sarium avenaceum hydroxylates formononetin in the 3'-position yielding 3',7-dihydroxy-4'-methoxyisoflavone (calycosin). 3'-Hydroxylation of biochanin A to 3/,5,7-trihydroxy-4/-methoxyisoflavone (pratensein) has been observed with Fusarium oxysporum f. sp. lycopersici and Fusarium oxysporum f. sp. I ini. Depending on the growth medium Fusarium proliferatum metabolises for mononetin either by 7-O-methylation or by 4'-0-demethylation.
منابع مشابه
3'-Hydroxylation of 4'-methoxyisoflavones by Fusarium oxysporum f. lycopersici.
3'-Hydroxylation of isoflavones by Fusarium oxysporum f. lycopersici mainly proceeds with 4'-methoxy-7-hydroxyderivatives; this reaction is used for quantitative conversion of 14C-labelled isoflavones.
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